Role of covalent modification by hepatic aldehydes in dictamnine-induced liver injury

In conclusion, the metabolic activation of the furan ring of dictamnine resulted in the protein adduction by multiple hepatic aldehydes and the protein modification played a crucial role in dictamnine-induced liver injury.PMID:38128889 | DOI:10.1016/j.toxlet.2023.12.010

Source: Toxicology Letters - December 21, 2023 Category: Toxicology Authors: Qi Luo Yang Shen Guohong Zhai Lin Chen Furong Ou Luxi Yi Danli Yang Hong Pan Fuguo Shi Source Type: research