The long-term impact of irradiation on functional connectivity in brain circuits involved in memory processes after pediatric posterior fossa tumor

Memory deficit is one of the main neurocognitive outcomes in pediatric posterior fossa tumor (PFT) survivors [1]. Impairments have been shown in declarative memory [2,3] depending mainly on the hippocampus and cortico-hippocampal circuit, in working memory [4 –6] depending mainly on the cerebellum and prefrontal areas, and in motor procedural memory [3,7] depending on the striatum and the cerebellum [8].

Source: Radiotherapy and Oncology - December 23, 2023 Category: Radiology Authors: Elo ïse BAUDOU, Patrice PERAN, Fatima TENSAOUTI, Germain ARRIBARAT, Jérémie PARIENTE, Nicolas COURBIERES, Lisa POLLIDORO, Anne-Isabelle BERTOZZI, Marion GAMBART, Annick SEVELY, Margaux ROQUES, Anne DUCASSOU, Jérémy DANNA, Jessica TALLET, Christelle D Tags: Original Article Source Type: research