Structure-Based Drug Design for Targeting IRE1: An in Silico Approach for Treatment of Cancer

Conclusion Our results revealed that designed compound 17 could inhibit
IRE1 activity. Therefore, this designed compound is a remarkable inhibitor of
IRE1 and introduces a promising therapeutic strategy for cancer treatment. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Drug Research - December 22, 2023 Category: Drugs & Pharmacology Authors: Poustforoosh, Alireza Faramarz, Sanaz Nematollahi, Mohammad Hadi Mahmoodi, Mehdi Azadpour, Mahdiyeh Tags: Original Article Source Type: research