Perfluorooctanoic acid (PFOA) exposure induces renal filtration and reabsorption disorders via downregulation of aquaporins

In conclusion, we demonstrate that PFOA exposure can damage the renal filtration barrier and reduce the expression level of AQPs in renal tissues, leading to renal filtration and reabsorption disorders.PMID:38123106 | DOI:10.1016/j.toxlet.2023.12.003

Source: Toxicology Letters - December 20, 2023 Category: Toxicology Authors: Li Wang Weiqiang Sun Xinzhuang Ma Nathan Griffin Hui Liu Source Type: research