Therapeutic Hope on the Surface of Ewing Sarcoma

Clin Cancer Res. 2023 Dec 19. doi: 10.1158/1078-0432.CCR-23-3138. Online ahead of print.ABSTRACTA detailed analysis of the Ewing sarcoma surfacesome has arrived. Robust expression of surface CDH11 and ENPP1 was identified. This "comprehensive catalogue" of the Ewing surfacesome serves as a fresh roadmap to development of new therapeutic approaches, including immunotherapies and multi-modality therapeutic combinations, to target aggressive Ewing tumor subpopulations.PMID:38113033 | DOI:10.1158/1078-0432.CCR-23-3138
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Source Type: research