Bacterial antigens unleash tumor-targeting immunity

Cell Host Microbe. 2023 Dec 13;31(12):1945-1947. doi: 10.1016/j.chom.2023.11.001.ABSTRACTThe composition of the gut microbiome has been shown to influence disease outcome in patients with colorectal cancer (CRC). In a recent Nature Biotechnology article, Wang et al. demonstrate that killing CRC-associated bacteria with a liposomal antibiotic elicits CRC-targeting immune responses of therapeutic relevance as a consequence of epitope mimicry.PMID:38096784 | DOI:10.1016/j.chom.2023.11.001

Source: Cell Host and Microbe - December 14, 2023 Category: Microbiology Authors: Nina Boeck Zlatko Trajanoski Lorenzo Galluzzi Source Type: research