Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016-2022

CONCLUSIONS: Future methods development should prioritize methods for SW-CRTs with binary or time-to-event outcomes, small numbers of clusters, continuous recruitment designs, multivariate outcomes, or time-dependent repeated measures. Trialists, journal editors, and peer reviewers should be aware that SW-CRTs have additional methodological requirements over parallel arm designs including the need to account for period effects as well as complex intracluster correlations.PMID:37990575 | DOI:10.1177/17407745231208397

Source: Clinical Trials - November 22, 2023 Category: Research Authors: Pascale Nevins Mary Ryan Kendra Davis-Plourde Yongdong Ouyang Jules Antoine Pereira Macedo Can Meng Guangyu Tong Xueqi Wang Luis Ortiz-Reyes Agn ès Caille Fan Li Monica Taljaard Source Type: research