Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells

Ephrin (EPH) receptors have been implicated in tumorigenesis and metastasis, but the functional understanding of mutations observed in human cancers is limited. We previously demonstrated reduced cell compartm...

Source: Cell Communication and Signaling - December 15, 2023 Category: Molecular Biology Authors: Snehangshu Kundu, Lu ís Nunes, Jeremy Adler, Lucy Mathot, Ivaylo Stoimenov and Tobias Sjöblom Tags: Research Source Type: research