Cytokines Expression Compared to the Determinants of Cellular Apoptosis Prominently Attributes to the Deleterious Effects of 'A' Determinant Surface Gene Mutations in HBV Transfected Hepatoma Cell Line

CONCLUSION: Cytokines expression predominantly contributes to the detrimental effects associated with the 'a' determinant region mutations particularly sG145R mutant. It may also be inferred that mechanisms associated with cellular apoptosis apparently do not play any major role to assign the 'a' determinant small surface gene mutation(s) for their pathological outcome.PMID:38095846 | DOI:10.1080/08820139.2023.2288841

Source: Immunological Investigations - December 14, 2023 Category: Allergy & Immunology Authors: Saniya Khan Ayesha Anwer Jayesh Kumar Sevak Nirupama Trehanpati Syed Naqui Kazim Source Type: research