New evidence of the impact of mitochondria on kidney health and disease

Nature Reviews Nephrology, Published online: 14 December 2023; doi:10.1038/s41581-023-00803-zSeveral publications from 2023 have substantiated the importance of altered NAD synthesis in kidney injury and disease progression. Now, NAD deficiency has been linked to the release of mitochondrial RNA and activation of pathways that induce inflammation. Another enzyme that governs mitochondrial function, PCK1, has also now been linked to kidney disease.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research