Altered glucagon and GLP-1 responses to oral glucose in children and adolescents with obesity and insulin resistance

CONCLUSIONS: The OIR-group had elevated fasting concentrations of glucagon and GLP-1, and higher glucagon, but lower GLP-1 responses during an OGTT compared to the OIS- and NW-groups. In contrast, the OIS-group had similar hormone responses to the NW-group.PMID:38087928 | DOI:10.1210/clinem/dgad728

Source: The Journal of Clinical Endocrinology and Metabolism - December 13, 2023 Category: Endocrinology Authors: Sara Elizabeth Stinson Ierai Fern ández de Retana Alzola Emilie Damgaard Br ünner Hovendal Morten Asp Vonsild Lund Cilius Esmann Fonvig Louise Aas Holm Anna Elisabet Jonsson Christine Frithioff-B øjsøe Michael Christiansen Oluf Pedersen Lars Ängquist Source Type: research