[Translated article] Pharmacokinetics of eculizumab in adult and pediatric patients with atypical hemolytic uremic syndrome and C3 glomerulopathy

CONCLUSIONS: The present study reports supratherapeutic concentrations of eculizumab in patients with aHUS, and defines higher concentrations than those described in the data sheet to achieve blockade, thus encouraging the personalization of treatment with eculizumab.PMID:38057242 | DOI:10.1016/j.farma.2023.09.009

Source: Farmacia Hospitalaria - December 6, 2023 Category: Drugs & Pharmacology Authors: Alba Pau Parra Natalia Ramos Janire Perurena-Prieto Silvia Manrique-Rodr íguez Monica Climente Laura Garc ía Quintanilla Ángel Escolano Marta Miarons grupo PK-ECU-ORPHAR Source Type: research