Lymphocyte transformation tests predict delayed-type allergy to piperacillin/tazobactam in patients with cystic fibrosis

Antibiotic treatment is crucial for patients with cystic fibrosis (CF) due to chronic bacterial lung infections. The prevalence of delayed-type allergic reactions such as skin rashes, drug fever and drug-induced liver injury is higher in CF than in the general population and forms a challenge for patients and caregivers [1 –3]. Past adverse reactions to specific drugs often cause an avoidance of the suspected allergic agent, frequently leading to a suboptimal choice of antibiotic treatment and to premature use of antibiotics of last resort.
Source: Journal of Cystic Fibrosis - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research