The Dosage Recommendation of Cyclosporin in Children with Hemophagocytic Lymphohistiocytosis Based on Population Pharmacokinetic Model

CONCLUSION: It is the first time that the cyclosporin dosage regimens for HLH in children have been developed based on Monte Carlo simulation, and the initial dosage optimizations of cyclosporine in pediatric HLH patients have been recommended.PMID:38062660 | DOI:10.2174/0113816128286290231124055116

Source: Current Pharmaceutical Design - December 8, 2023 Category: Drugs & Pharmacology Authors: Yang Yang Ya-Feng Li Ke Hu Shi-Jia Zhang Jia-Fang Cui Xue-Ting Huang Su-Mei He Dong-Dong Wang Xiao Chen Source Type: research