Bioavailability and daily requirement of vitamin B < sub > 12 < /sub > in adult humans: an observational study of its colonic absorption and daily excretion as measured by [ < sup > 13 < /sup > C]-cyanocobalamin kinetics

CONCLUSIONS: B12 is absorbed in the human colon. This observation confirms the potential contribution of the colon in daily B12 nutriture, and along with a possible lower requirement, could explain the absence of clinical deficiency in populations with marginal B12 intakes.TRIAL REGISTRATION NUMBER: This study was registered in Clinical Trials Registry of India (CTRI) with the registration number CTRI/2018/04/012957, available from https://ctri.nic.in/Clinicaltrials/showallp.php?mid1=49319&EncHid=&userName=029108.PMID:38044024 | DOI:10.1016/j.ajcnut.2023.08.020

Source: Am J Clin Nutr - December 3, 2023 Category: Nutrition Authors: Anura V Kurpad Roshni M Pasanna Shalini G Hegde Mallikarjun Patil Arpita Mukhopadhyay Harshpal S Sachdev Kishor G Bhat Ambily Sivadas Sarita Devi Source Type: research