Chemokine receptor CCR1 regulates macrophage activation through mTORC1 signaling in nonalcoholic steatohepatitis

Chemokine (CC motif) receptor 1 (CCR1) promotes liver fibrosis in mice. However, its effects on nonalcoholic steatohepatitis (NASH) remain unclear. Therefore, the present study aimed to investigate the role of CCR1 in the progression of NASH.

Source: Metabolism - Clinical and Experimental - December 7, 2023 Category: Biomedical Science Authors: Haoran Li, Tongtong Pan, Lingjia Gao, Rongxiu Ding, Yanwen Yu, Mengchen Ma, Yajiao Wang, Shengnan Jin, Yongping Chen, Chunming Ding, Liang Xu Source Type: research