Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients

ConclusionIn conclusion, CLS were more frequently present in breast adipose tissue of breast cancer patients compared toBRCA1/2 gene mutation carriers and healthy controls. Furthermore, our study provides evidence of the association between obesity and presence of CLS. The prognostic significance and impact on clinical outcome of differences in CLS numbers should be further assessed in prospective studies.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research