Mixture modelling of < em > Bordetella pertussis < /em > serology samples to evaluate anti-pertussis toxin immunoglobulin G titre thresholds for positivity: England 2008-2022

Conclusion. Mixture modelling is a useful tool to establish thresholds, but reassessment should also be done when there have been changes to prevalence and/or testing regimes to determine whether there have been any changes in sensitivity, specificity, PPV, and NPV and whether the threshold should be revised.PMID:38047762 | DOI:10.1099/jmm.0.001774

Source: Journal of Medical Microbiology - December 4, 2023 Category: Microbiology Authors: Elise Tessier David Litt Sonia Ribeiro Nurin Abdul Aziz Helen Campbell Gayatri Amirthalingam Norman K Fry Nick Andrews Source Type: research