Senescent cells in giant cell arteritis display an inflammatory phenotype participating in tissue injury via IL-6-dependent pathways

CONCLUSIONS: Senescent cells with inflammatory phenotype are present in GCA arteries and are associated with the tissue inflammatory bulk, suggesting a potential implication in disease pathogenesis.PMID:38050005 | DOI:10.1136/ard-2023-224467

Source: Cancer Control - December 5, 2023 Category: Cancer & Oncology Authors: Dimitris Veroutis Ourania D Argyropoulou Andreas V Goules Konstantinos Kambas Dimitris Anastasios Palamidas Konstantinos Evangelou Sophia Havaki Aikaterini Polyzou Dimitrios Valakos Evangelia Xingi Elli Karatza Kyriaki A Boki Alberto Cavazza Christos Kitt Source Type: research