FGF-independent MEK1/2 signalling in the developing foetal testis is essential for male germline differentiation in mice

Disrupted germline differentiation or compromised testis development can lead to subfertility or infertility and are strongly associated with testis cancer in humans. In mice, SRY and SOX9 induce expression of Fg...

Source: BMC Biology - December 5, 2023 Category: Biology Authors: Rheannon O. Bl ücher, Rachel S. Lim, Ellen G. Jarred, Matthew E. Ritchie and Patrick S. Western Tags: Research article Source Type: research