Western diet prevents intestinal inflammation and fibrosis in a dss-induced model of colitis

Rationale: Intestinal fibrosis is a major complication of inflammatory bowel diseases (IBD) and remains without specific treatment. Because western dietary pattern is associated with increased IBD incidence and promotes extra-intestinal fibrosis, we hypothesized that western diet (WD) may influence intestinal fibrosis development. The aim was to assess WD consumption on inflammation and intestinal fibrosis in murine colitis models.

Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: M. Leboutte, E. Rebollo, C. Pangault, C. Gu érin, C. Bôle-Feysot, M. Monnoye, P. Gérard, G. Savoye, R. Marion-Letellier Source Type: research