Cancer-associated cachexia: Evaluation of lipolysis markers by QRT-PCR in subcutaneous adipose tissue of gastrointestinal cancer patients

Rationale: Enhanced lipolysis and inhibition of adipogenesis are implicated in adipose tissue loss in cachexia. However, these mechanisms are not completely clarified in patients with cancer. We investigated the expression levels of lipolysis-associated genes in subcutaneous adipose tissue (SAT) in newly diagnosed gastrointestinal (GI) cancer patients according to the presence/absence of cachexia

Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Molfino, G. Imbimbo, F. Tambaro, E. Ferraro, G. Lauteri, M. Andreini, M. Melena, M.I. Amabile, G. Nigri, M. Muscaritoli Source Type: research