Base editing therapy corrects long QT syndrome in mice

Nature Reviews Cardiology, Published online: 05 December 2023; doi:10.1038/s41569-023-00977-wGene therapy involving adenine base editing can correct a pathogenic variant in the Scn5a gene and alleviate arrhythmia phenotypes in a mouse model of long QT syndrome type 3.

Source: Nature Reviews Cardiology - December 5, 2023 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research