Reliability and Responsiveness of Histologic Indices for the Assessment of Crohn ’s Disease Activity

The operating properties of histologic indices for evaluating Crohn ’s disease (CD) activity are poorly characterized. We assessed the reliability and responsiveness of existing histologic indices/items used in CD and ulcerative colitis (UC), in addition to 3 novel items, and developed exploratory ileal, colonic, and colonic-ileal CD instruments.

Source: Clinical Gastroenterology and Hepatology - December 3, 2023 Category: Gastroenterology Authors: Virginia Solitano, David F. Schaeffer, Malcolm Hogan, Niels Vande Casteele, Rish K. Pai, Guangyong Zou, Reetesh K. Pai, Claire E. Parker, Julie R émillard, Britt Christensen, Silvio Danese, Laurent Peyrin-Biroulet, Remo Panaccione, Bruce E. Sands, Geert Source Type: research