Utilize polygenic risk score to enhance fracture risk estimation and improve the performance of FRAX in patients with osteoporosis

ConclusionsOur study highlights the potential of PGS to augment fracture risk estimation in conjunction with FRAX, particularly in individuals with middle to low risks. Incorporating genetic testing could empower physicians to tailor personalized preventive strategies for osteoporosis.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research