Molecular Markers Are Associated with Onset of Radioiodine Refractoriness in Patients with Papillary Thyroid Carcinoma

Conclusion: Our data show a significant association between the onset of RR-TC and mutations in telomerase reverse transcriptase promoter and tumor protein 53, indicating the need for a more extensive diagnostic workup in these patients. Certain genetic changes put patients with thyroid cancer at risk of developing cancer spread that does not respond to radioiodine therapy.

Source: Journal of Nuclear Medicine - December 1, 2023 Category: Nuclear Medicine Authors: Laschinsky, C., Theurer, S., Herold, T., Rawitzer, J., Weber, F., Herrmann, K., Brandenburg, T., Fuhrer-Sakel, D., Fendler, W. P., Weber, M. Tags: Brief Communications Source Type: research