M2 macrophage-derived exosomes induce angiogenesis and increase skin flap survival through HIF1AN/HIF-1 α/VEGFA control

CONCLUSION: This study showed that M2-exosomes promote skin flap survival by enhancing angiogenesis, with HIF1AN/HIF-1α/VEGFA playing a crucial role in this process.PMID:38030054 | DOI:10.1016/j.abb.2023.109822

Source: Archives of Biochemistry and Biophysics - November 29, 2023 Category: Biochemistry Authors: Gaojie Luo Zekun Zhou Zheming Cao Chengxiong Huang Cheng Li Xiaoxiao Li Chao Deng Panfeng Wu Zhenni Yang Juyu Tang Liming Qing Source Type: research