SARS-CoV-2 infection in solid organ transplant recipients: Experience with molnupiravir

Rev Esp Quimioter. 2023 Nov;36 Suppl 1:22-24. doi: 10.37201/req/s01.06.2023. Epub 2023 Nov 24.ABSTRACTSolid organ transplant recipients (SOTR) constitute one of the groups at highest risk for the development of severe COVID-19. However, evidence on the effectiveness of treatments for SARS-CoV-2 infection in this group of patients is scarce. Molnupiravir is an orally administered antiviral drug that has demonstrated effectiveness in reducing the risk of progression to severe COVID-19 in high-risk outpatients, mainly in the unvaccinated population. Although its effectiveness is lower than that of other antivirals, on many occasions it is the only therapeutic option in transplant recipients given the absence of pharmacological interactions with immunosuppressive treatment, the oral route of administration and the good safety profile.PMID:37997866 | DOI:10.37201/req/s01.06.2023
Source: Revista Espanola de Quimioterapia - Category: Drugs & Pharmacology Authors: Source Type: research