Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson ’s disease in rodent brains

Alpha-synuclein ( α-syn) aggregation into proteinaceous intraneuronal inclusions, called Lewy bodies (LBs), is the neuropathological hallmark of Parkinson’s disease (PD) and related synucleinopathies. However, ...

Source: Molecular Neurodegeneration - November 27, 2023 Category: Neurology Authors: Morgan B érard, Laura Martínez-Drudis, Razan Sheta, Omar M. A. El-Agnaf and Abid Oueslati Tags: Research article Source Type: research