New perspectives in late-onset multiple acyl-CoA dehydrogenase deficiency: Clinical and genetic findings

In the realm of neuromuscular disorders, late-onset myopathies, particularly those manifesting in the seventh or eighth decade of life, have often presented a diagnostic and therapeutic challenge [1]. In this group of diseases, late-onset multiple acyl-CoA dehydrogenase deficiency (MADD) is included. It is a less severe, yet clinically significant form of MADD. Unlike its neonatal counterparts, late-onset MADD presents in childhood, adolescence, or even adulthood, and is characterized by a more variable and often milder symptomatology [2].
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Source Type: research