Electrical Impedance Tomography Identifies Evolution of Regional Perfusion in a Porcine Model of Acute Respiratory Distress Syndrome

ConclusionsElectrical impedance tomography closely approximated computed tomography perfusion measures in experimental acute respiratory distress syndrome, in the supine position, over injury progression and with increased PEEP. Further validation is needed to determine the accuracy of electrical impedance tomography in measuring perfusion redistributions after positional changes.Editor ’s PerspectiveWhat We Already Know about This TopicIn patients with acute respiratory distress syndrome, alterations in regional pulmonary perfusion may markedly alter global oxygenation and have important clinical ramifications for the use of varying levels of positive end-expiratory pressure or positional therapyContrast enhanced computed tomography has generally been considered the clinical gold standard for assessing ventilation-to-perfusion relationships, but the less invasive, radiation-free, and logistically less intensive technology, electrical impedance tomography, has been suggested as a viable alternativeQuantitative data on electrical impedance tomography ’s accuracy relative to computed tomography perfusion imaging have not been well delineatedWhat This Article Tells Us That Is NewUsing a porcine model of acute lung injury, the authors compared electrical impedance tomography and computed tomography perfusion images in eight vertical regions obtained at two injury time points in 11 animals, as well as in response to increasing positive end-expiratory pressure, and in eight ani...
Source: Anesthesiology - Category: Anesthesiology Source Type: research