Flexible Gel-Free Multi-Modal Wireless Sensors With Edge Deep Learning for Detecting and Alerting Freezing of Gait Symptom

Freezing of gait (FoG) is a debilitating symptom of Parkinson's disease (PD). This work develops flexible wearable sensors that can detect FoG and alert patients and companions to help prevent falls. FoG is detected on the sensors using a deep learning (DL) model with multi-modal sensory inputs collected from distributed wireless sensors. Two types of wireless sensors are developed, including: 1) a C-shape central node placed around the patient's ears, which collects electroencephalogram (EEG), detects FoG using an on-device DL model, and generates auditory alerts when FoG is detected; 2) a stretchable patch-type sensor attached to the patient's legs, which collects electromyography (EMG) and movement information from accelerometers. The patch-type sensors wirelessly send collected data to the central node through low-power ultra-wideband (UWB) transceivers. All sensors are fabricated on flexible printed circuit boards. Adhesive gel-free acetylene carbon black and polydimethylsiloxane electrodes are fabricated on the flexible substrate to allow conformal wear over the long term. Custom integrated circuits (IC) are developed in 180 nm CMOS technology and used in both types of sensors for signal acquisition, digitization, and wireless communication. A novel lightweight DL model is trained using multi-modal sensory data. The inference of the DL model is performed on a low-power microcontroller in the central node. The DL model achieves a high detection sensitivity of 0.81 and a ...
Source: IEEE Transactions on Biomedical Circuits and Systems - Category: Biomedical Engineering Source Type: research