Molecular Dynamics of a N-Cyclohexyl-1,2,4-Oxadiazole Derivative as a Reversible Cruzain Inhibitor in Trypanosoma cruzi

CONCLUSION: Finally, the findings indicate that the investigated molecule 2b can interfere enzymatic activity of cruzain, indicating that it might be a promising antichagasic drug.PMID:37957896 | DOI:10.2174/0113862073268297231025110913

Source: Combinatorial Chemistry and High Throughput Screening - November 14, 2023 Category: Chemistry Authors: Yasmim Mendes Rocha Gabriel Ac ácio de Moura Jo ão Pedro Viana Rodrigues Cristian Vicson Gomes Pinheiro Ronaldo Nascimento de Oliveira Marcia Machado Marinho Roberto Nicolete Source Type: research