Association of sex-specific abdominal adipose tissue with WHO/ISUP grade in clear cell renal cell carcinoma

ConclusionsIntermuscular fat index proved to be a valuable biomarker for the pathological grade of ccRCC and could be used as a reliable independent predictor of high-grade ccRCC for both males and females.Critical relevance statementSex-specific fat adipose tissue can be used as a new biomarker to provide a new dimension for renal tumor-related research and may provide new perspectives for personalized tumor management decision-making approaches.Key points• There are sex differences in distribution of subcutaneous fat and visceral fat.• The SFI, VFI, TFI, and rVAT were significantly lower in high-grade ccRCC male patients, but not for female patients.• Intermuscular fat index can be used as a reliable independent predictor of high-grade ccRCC for both males and females.Graphical Abstract
Source: Insights into Imaging - Category: Radiology Source Type: research