Osthole inhibits GSK-3 β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice

ConclusionOsthole has a  radiosensitizing effect on subcutaneous transplanted hepatocellular carcinoma, and its mechanism may be related to inhibition of GSK-3β/AMPK/mTOR pathway-controlled glycolysis.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research