One receptor, two worlds: MXRA8's alphavirus tango

Cell Host Microbe. 2023 Nov 8;31(11):1763-1764. doi: 10.1016/j.chom.2023.10.008.ABSTRACTMammalian MXRA8 functions as a receptor for chikungunya and other related alphaviruses. A recent study in Cell molecularly characterizes host-specific receptor usage, specifically showing avian MXRA8 acts as a receptor for several alphaviruses with avian reservoirs in an inverted manner relative to alphaviruses that use mammalian MXRA8 as a receptor.PMID:37944485 | DOI:10.1016/j.chom.2023.10.008
Source: Cell Host and Microbe - Category: Microbiology Authors: Source Type: research