An engineered Escherichia coli Nissle strain prevents lethal liver injury in a mouse model of tyrosinemia type 1

In this study, we aimed to construct an engineered bacterium capable of reprogramming host metabolism and thereby provide a potential alternative approach for the treatment of HT1.

Source: Journal of Hepatology - November 10, 2023 Category: Gastroenterology Authors: Peng Gu, Li Xie, Tao Chen, Qin Yang, Xianglong Zhang, Ruofan Liu, Jiayin Guo, Rongjuan Wei, Dongping Li, Yong Jiang, Ye Chen, Wei Gong, Peng Chen Tags: Research Article Source Type: research