N-glycosylation in Archaea: Unusual sugars and unique modifications

Carbohydr Res. 2023 Oct 5;534:108963. doi: 10.1016/j.carres.2023.108963. Online ahead of print.ABSTRACTArchaea are microorganisms that comprise a distinct branch of the universal tree of life and which are best known as extremophiles, residing in a variety of environments characterized by harsh physical conditions. One seemingly universal trait of Archaea is the ability to perform N-glycosylation. At the same time, archaeal N-linked glycans present variety in terms of both composition and architecture not seen in the parallel eukaryal or bacterial processes. In this mini-review, many of the unique and unusual sugars found in archaeal N-linked glycans as identified by nuclear magnetic resonance spectroscopy are described.PMID:37890267 | DOI:10.1016/j.carres.2023.108963
Source: Carbohydrate Research - Category: Genetics & Stem Cells Authors: Source Type: research