AI-driven Discovery of Celecoxib and Dexamethasone for Exploring their Mode of Action as Human Interleukin (IL-6) Inhibitors to Treat COVID-19-induced Cytokine Storm in Humans

CONCLUSION: The findings of this study have suggested the potential of the drugs studied to be utilized as antagonists for countering CRS in COVID-19 ailment. This study presents the studied drugs as promising candidates both for the clinical and pre-clinical treatment of COVID-19.PMID:37921134 | DOI:10.2174/0113816128260449231017091824

Source: Current Pharmaceutical Design - November 3, 2023 Category: Drugs & Pharmacology Authors: Israa M Shamkh Mahmoud Elkazzaz Enas S Radwan Jawayria Najeeb Md Tabish Rehman Mohamed F AlAjmi Moayad Shahwan Muhammad Sufyan Nouf Khaifa Alaqeel Ibrahim A Ibrahim Basit Jabbar Mohammad Shahbaz Khan Tomasz M Karpi ński Ishrat Rahman Abdullah Haikal Reem Source Type: research