SLC38A5 promotes glutamine metabolism and inhibits cisplatin chemosensitivity in breast cancer

CONCLUSION: Our findings suggest that SLC38A5 enhances BC cell viability by glutamine metabolism, inhibits the chemical sensitivity of cisplatin in BC cells, and promotes tumor growth, emphasizing the clinical relevance of SLC38A5 in BC management as a novel potential therapeutic target.PMID:37914960 | DOI:10.1007/s12282-023-01516-8

Source: Breast Cancer - November 2, 2023 Category: Cancer & Oncology Authors: Xiaowei Shen Ganggang Wang Hua He Ping Shang Bin Yan Xiaoliang Wang Weixing Shen Source Type: research