Sex differences in energy metabolism: natural selection, mechanisms and consequences

Nature Reviews Nephrology, Published online: 03 November 2023; doi:10.1038/s41581-023-00781-2In this Review, Franck Mauvais-Jarvis discusses how adaptive selection during evolution could have shaped sex differences in energy partitioning, adipose tissue function and distribution, and glucose homeostasis. He also discusses the hormonal and genetic mechanisms that underlie these sex differences and their implications for metabolic disease and sex-based precision medicine.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research