Saikosaponin-d regulates angiogenesis in idiopathic pulmonary fibrosis through angiopoietin/Tie-2 pathway

CONCLUSION: This study has demonstrated that SSd could down-regulate the expression of ANG-1, Ang-2 and Tie2 in the Ang/Tie2 pathway, and may reduce lung inflammation and PF in BLM-induced mice via inhibition of angiogenesis.PMID:37837833 | DOI:10.1016/j.acthis.2023.152100

Source: Acta Histochemica - October 14, 2023 Category: Biochemistry Authors: Yan Wu Jun Zhang Xintian Wang Yuncong Xu Jinxu Zheng Source Type: research