Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases

Cui et  al. identify hyperoxidized PRDX3 as a marker for ferroptosis both in vitro and in vivo. Applying this marker, they demonstrate that hepatic damage in mouse models of AFLD and NAFLD, the most prevalent chronic liver diseases in humans, is caused by ferroptosis.

Source: Molecular Cell - October 19, 2023 Category: Cytology Authors: Shaojie Cui, Anchal Ghai, Yaqin Deng, Shili Li, Ruihui Zhang, Christopher Egbulefu, Guosheng Liang, Samuel Achilefu, Jin Ye Tags: Short article Source Type: research