Anxiety Change After Dopamine Therapy in Parkinson Disease is Independent of Motor Improvement

CONCLUSION: Dopamine repletion effected immediate relief of anxiety in an On-Off state comparison. A similar benefit was observed in the longitudinal PPMI cohort by comparing anxiety before and after DRT initiation, suggesting DRT confers sustained anxiolytic effects in early PD. The weak correlations between improvements to anxiety and motor function on both timescales support the view that these changes are not mediated by improved motor function.PMID:37867011 | DOI:10.1016/j.jagp.2023.09.001
Source: Am J Geriatr Psychia... - Category: Geriatrics Authors: Source Type: research