PARAKID: Navigating the relation between paraproteins and kidney lesions: A multi-center retrospective observational study

CONCLUSION: Paraproteinemia is associated with a myriad of kidney lesions. MGRS and MM are usually present in the 6th decade of life and beyond, while proliferative glomerulonephritis with monoclonal immunoglobulin deposits is more common in the younger age group. Older age group, high creatinine, hyperuricemia, hyperphosphatemia, presence of more than one lesion on kidney biopsy, and presence of cast nephropathy was significantly associated with the requirement of kidney replacement therapy.PMID:37870264 | DOI:10.5414/CN111123
Source: Clinical Nephrology - Category: Urology & Nephrology Authors: Source Type: research