Core genome multilocus sequence typing of Clostridioides difficile to investigate transmission in the hospital setting

ConclusionAmong clusters determined by cgMLST analysis, roughly 40% included unexplained HA-CDI acquisitions, which may be explained by unidentified epidemiological links, asymptomatic colonization, and/or shared common community reservoirs. The use of DLST, followed by whole genome sequencing analysis, is a promising and cost-effective stepwise approach for the investigation of CDI transmission in the hospital setting.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research