Control of mitochondrial dynamics by a fusogenic lipid

Trends Cell Biol. 2023 Oct 17:S0962-8924(23)00210-6. doi: 10.1016/j.tcb.2023.10.006. Online ahead of print.ABSTRACTMitochondrial fusion enables cooperation between the mitochondrial population and is critical for mitochondrial function. Phosphatidic acid (PA) on the mitochondrial surface has a key role in mitochondrial fusion. A recent study by Su et al. shows that the nucleoside diphosphate (NDP) kinase NME3 recognizes PA and mediates its effects on mitochondrial dynamics.PMID:37858503 | DOI:10.1016/j.tcb.2023.10.006

Source: Trends in Cell Biology - October 20, 2023 Category: Cytology Authors: Zheng Yang David C Chan Source Type: research