Intraretinal pigmented cells in retinal degenerative disease

Conclusions
Our findings suggest that RPE cells invading the retina dedifferentiate (losing classic RPE markers) and can be pigmented or unpigmented. Therefore, the number of RPE cells invading the retina in retinal degenerative disease may be underappreciated by funduscopy.

Source: British Journal of Ophthalmology - October 20, 2023 Category: Opthalmology Authors: Yasvoina, M., Yang, Q., Woods, S. M., Heeren, T., Comer, G. M., A. Egan, C., Fruttiger, M. Tags: Original articles - Laboratory science Source Type: research