A protective role of low polygenic risk score in healthy individuals carrying ADHD-associated CNVs

Previous studies have implicated both rare copy number variations (CNVs) and common variants in liability for Attention deficit hyperactivity disorder (ADHD). However, how common and rare genetic variants jointly contribute to individual liability requires further investigation in larger cohorts.

Source: Biological Psychiatry - October 19, 2023 Category: Psychiatry Authors: Xiao Chang, Huiqi Qu, Yichuan Liu, Joseph Glessner, Hakon Hakonarson Tags: Archival Report Source Type: research