The Role of the IL-33/ST2 Axis in CpG-Induced Macrophage Activation Syndrome

CONCLUSION: These results suggested that IL-33 decreased in the liver and spleen tissues of MAS mice. Further results suggest that IL-33 and St2 knockout mice have no treatment potential in CpG-induced MAS. Thus, the IL-33/ST2 axis has little effect on the prognosis of CpG-induced MAS.PMID:37842289 | PMC:PMC10569892 | DOI:10.1155/2023/2689360
Source: Journal of Immunology Research - Category: Allergy & Immunology Authors: Source Type: research